A Boeing 737 airliner from Cuba’s state airline Cubana de Aviacion has crashed and exploded near Jose Marti International Airport in Havana, Cuban media report.
The plane came down shortly after take-off, Prensa Latina news agency said.
Radio Habana Cuba said it was an internal flight from the Cuban capital to Holguin, in the east of the island.
Witnesses told AFP news agency they could see a thick column of smoke near the airport.
Fire crews and ambulances are reported to be at the scene.
Radio Habana Cuba said on Twitter that the plane came down on the “highway” between Boyeros and Havana, near the airport.
Cuba’s president Miguel Diaz-Canel, who was sworn in last month, is said to be en route to the scene, AFP reports.
More than 100 people on board plane that crashed
From CNN’s Patrick Oppmann and Marilia Brocchetto
Cuban state media reports that there were 104 people on board a plane that crashed shortly after takeoff at Havana’s airport.
Boeing 737 plane was heading to the Cuban city of Holguin.